Methacrylamide (chemical formula: C₄H₇NO, CAS: 79-39-0) is an organic compound with diverse functionalities across multiple industries. Its molecular structure enables controlled reactivity, making it suitable for synthesizing polymers, biomaterials, and specialty chemicals. Below is a detailed overview of its validated applications:  

 1. Biomedical and Pharmaceutical Fields  

- Tissue Engineering & Regenerative Medicine: Methacrylamide-modified gelatin (GelMA) forms photo-crosslinkable hydrogels for wound dressings, and scaffolds for bone/cartilage repair. These hydrogels support cell adhesion, proliferation, and controlled biodegradation .  

- Drug Delivery Systems: GelMA hydrogels enable sustained release of therapeutic agents (e.g., antibiotics) due to their tunable mechanical properties and biocompatibility .  

- Medical Devices: Used in coatings for implants (e.g., cardiac stents) and surgical adhesives for sealing tissue leaks, enhancing biocompatibility and reducing inflammation .  

 2. Textile and Sericulture Processing  

- Silk Weighting Agent: Compensates for 20%–30% weight loss in raw silk during degumming. Improves luster, texture, and dye affinity of silk fabrics .  

- Dyeing Auxiliary: Enhances pigment dispersion, color fastness, and wash/scrub resistance in textiles. Reduces environmental impact compared to formaldehyde-based alternatives .  

- Fiber Modifier: Functions as an antistatic agent, humectant, and softener in synthetic fibers .  

 3. Chemical Intermediates for Polymer Synthesis  

- Methyl Methacrylate (MMA) Production: Serves as a precursor for MMA, a key monomer in acrylic plastics, coatings, and adhesives .  

- High-Performance Coatings: Incorporated into elastic exterior wall paints for improved weather resistance and adhesion .  

 4. Environmentally Friendly Adhesives and Resins  

- Crosslinking Monomer: Derivatives like N-(Isobutoxymethyl)acrylamide (IBMA) enhance water/solvent resistance in acrylic emulsions for eco-friendly flocking adhesives, leather finishes, and textile binders—without releasing formaldehyde .  

 5. Material Properties and Safety  

- Physical Traits: White crystalline solid (slightly yellow in industrial grade), melting point 108°C, soluble in water and ethanol .  

- Storage: Stable under cool, dry, and ventilated conditions; packaged in 25 kg bags .  

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Methacrylamide’s adaptability stems from its dual reactivity (amide and vinyl groups), enabling innovation in sustainable materials and life sciences. Compliance with industrial safety and environmental standards ensures broad applicability without compromising regulatory requirements. For technical details or sourcing, refer to certified suppliers .